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| J. Egypt Vet. Med. Ass. 61. no 1: 45-55, 2001
Studies on the effect of theileria infection on the immunity of sheep
vaccinated with sheep pox vaccine
Samir, S.S. Zaki, F.F. Hegazy, N.A. and michael, A.
Veterinary Serum and Vaccine Research Institute,Abbassia, Cairo.
Central Laboratory for control of Veterinary Biologics, Abbasia, Cairo.
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The effect of theileria infection on the immunity produced by sheep pox vaccine was studicd. Fourteen susceptible sheep were divided into 5 groups , four of them were inoculated either with sheep pox vaccine alone or simulatneously with theileria infection (acute or samples, blood and lymph node smears were collected from the tested sheep during the experiment.
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The results abtained by challenge, serum neultralization and indirect fluorescent antibody tests revealed that the sheep antibody levels were highly depressed in the group actually infected with theeileria two weeks before vaccination, where their sera produced low neutralizing index (<1.5) and they showed postive reactions to challenge with virulent sheep pox virus.
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The same as the control groups 0 The other two groups of sheep either infected with chronic theileriosis or acute theeileriosis at the same time of vaccination showed partial supperssion of the antibody levels and their neutralizing indices remained still protective and resisted the challenge with virulent sheep pox virus.
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