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| The Egyptian Journal of immunologyVol.11 (1).2004
The production and Evaluation of a standard diagnostic paste des petits ruminants (PPR)
hyperimmune serm prepared from the Egyptian antigen ( Egypt 87)
Nahed,A. Kamel; Hanan,S .Abdel-Raouf; Hanan,
M.S. EL-Zawahry; Laila,A. Sedeek and Fatma, S.Mohamed
Veterinary Serum and Vaccine Research Institute,Abbassia, Cairo , Egypt.
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| Summary |
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The aim of this study was to produce a specific hyperimmune serum for diagnosis of peste des petits ruminants (PPR) . Based on good laboratory practices and standard operating procedures,we produced this reagent in goats using attenuated local strain of PPRV.
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The quality was assured to meet the internationally required levels of potency and sterility . The titer of the product was 10 2.4 as evaluated by virus neutrailzation (YN) and agar gel immunodiffusion (AGID) tests.
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In its final form, it is a sterile disc of a lyophilized material with a pale yellow colour, placed into an evacuated , tightly capped and capsulated vial . Local availability of such a product could be of great benefit at the time of need.
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