..::Veterinary Serum and Vaccine Research Institute::..

Beni-Suef Vet.Med.J.Vol. Xl ., No. (2) Oct., 2001 : (465 –477).

Isolation of the Causative agent of Harpo Pad Disease in Cats
(Canine Distemper in cats Apreliminary study to prepare a specific Vaccine)

Guirguis , W.I.:Azab, A.M.: Khodeir, M.H. and Daoud ,A.M.

Veterinary Serum and Vaccine Research Institute, Abbassia.Cairo.

Summary

	In the present study , it was noticed that a stray cat showed signs of illness (weakness and slight nasal discharges.) . It was cathed and subjected to clinical examination. Fever (41 o c ). Nasal discharges.

	Skin vesicles on the prened region and hard pad formation in the four limbs were observed. The cat was died and subjected to post mortem examination-immunohistopathological studies and trials for the isolation of the causative agent.

	The results of virus neutralization test and fluorescent microscopy revealed that the causative agent was canine distemper (CD) virus. So . cats could play a role in the epidemiology of CD and should be vaccinated against the disease . It is the first time to isolate CD virus from cats in Egypt . The obtained isolate named canine distemper virus (feline strain ) Abbassia/2001.