Susceptibility of camel and sheep to infection with foot and mouth disease virus F.M.D.V

A.A.M. Moussa A. Daoud S. Tawfik M. Arafa M. Amer

Central Laboratory for Evaluation of Veterinary Biologics

Abbassia, Cairo , Egypt.
Summary
 


Non-immunized , vaccinated and recovered camels and rams were inoculated intranasally with a fixed dose of FMDV of 10 7 MLD 80 per animls. Samples of oesophageal- Pharyngeal (OP) fuild were taken periodically as early as one hour post-infection till some weeks later on. The pharyngeal FMDV growth curves and the carrier state in the three inoculated group of both species of animals were also studied

In non immunized camels and rams:
Camels did not show any clinical symptoms of FMD or increase in the body temperature after exposure to infection On the contrary, the infected rams developed clinical signs and body temperature.

 
 
 


Pharyngeal virus growth curves for inoculated camels was more or less smooth with a peak infective titre achieved from 48 hours to 6 days post-infection. On the other hand, the growth curve of FMDV replication in the pharyrgeal region of infected rams was consisted of series with a maximum titre obtained at 24 and 48 hours post-infection .

In vaccinated camels and rams:
The pharyngeal virus was firstly detected one hour post-exposure of camels to FMDV infection. This was followed by succesive isolation of FMDV for a preiod of 24 hours, after which the virus isolation was not running smoothly from the both time of isolation and virus titer point of views.

 
 
 


Contray to camels, the virus could be easily isolated from op. samples collected from ecposed rams to FMD infection in a titer ranging between 2-2.5 log 10 TCID 50 / m followed by smooth virus isolations of FMDV with some peaks in its titer at the 3 rd and 24 th hours post-exposure.

In recovered camels and rams:
In camels, the isolation of pharyngeal FMDV was delayed somewhat than that isolated from non immunized and immunized camels. The virus was being isolated at varying titers started from 6-24 hours post-re-exposure and lasted for up to 6 days. The same observation was also seen in re-exposed rams to infection with only considerable higher virus titer.